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Masana kimiyyar halittu suna buƙatar yin ƙari don haɓaka dacewa da sake haifuwa na binciken al'adun tantanin halitta.

Muna amfani da kukis don haɓaka ƙwarewar ku.Ta ci gaba da bincika wannan gidan yanar gizon, kun yarda da amfani da kukis.Karin bayani.
Akwai buƙatar gaggawa don rahotannin binciken ilimin halittu na ƙwayoyin dabbobi masu shayarwa su kasance masu daidaitawa da cikakkun bayanai, kuma don ingantaccen sarrafawa da auna yanayin muhalli na al'adun tantanin halitta.Wannan zai sa ƙirar ilimin halittar ɗan adam ya fi dacewa kuma yana ba da gudummawa ga sake fasalin bincike.
Tawagar masana kimiyyar KAUST da abokan aikinta a Saudi Arabiya da Amurka sun binciki takardu 810 da aka zabo bazuwar kan layukan kwayoyin halitta masu shayarwa.Kasa da 700 daga cikinsu sun haɗa da gwaje-gwajen al'adun cell guda 1,749, gami da bayanai masu dacewa kan yanayin muhalli na matsakaicin al'adun tantanin halitta.Binciken ƙungiyar ya nuna cewa ana buƙatar ƙarin aiki don inganta dacewa da sake fasalin irin waɗannan karatun.
Ƙirƙirar sel a cikin incubator mai sarrafawa bisa ga daidaitattun ladabi.Amma sel za su yi girma kuma suna "numfashi" na tsawon lokaci, suna musayar gas tare da yanayin da ke kewaye.Wannan zai shafi yanayin gida da suke girma a cikinsa, kuma yana iya canza acidity na al'ada, narkar da iskar oxygen, da ma'aunin carbon dioxide.Waɗannan canje-canje suna shafar aikin tantanin halitta kuma suna iya sanya yanayin jiki ya bambanta da yanayin jikin ɗan adam mai rai.
"Bincikenmu ya jaddada yadda masana kimiyya suka yi watsi da kulawa da kuma kula da yanayin salon salula, da kuma yadda rahotanni ke ba su damar cimma sakamakon kimiyya ta hanyoyi na musamman," in ji Klein.
Alal misali, masu bincike sun gano cewa kusan rabin takardun nazarin sun kasa bayar da rahoton yanayin zafin jiki da kuma saitunan carbon dioxide na al'adun kwayoyin su.Kasa da 10% sun ba da rahoton abun ciki na iskar oxygen a cikin incubator, kuma ƙasa da 0.01% sun ba da rahoton acidity na matsakaici.Babu wata takarda da aka ruwaito akan narkar da iskar oxygen ko carbon dioxide a cikin kafofin watsa labarai.
Mun yi mamaki sosai cewa masu bincike sun yi watsi da abubuwan da suka shafi muhalli da ke kula da matakan da suka dace da ilimin lissafin jiki a yayin duk tsarin al'adun tantanin halitta, irin su acidity na al'ada, ko da yake an san cewa wannan yana da mahimmanci ga aikin salula.”
Tawagar tana karkashin jagorancin Carlos Duarte, masanin ilimin halittu na ruwa a KAUST, da Mo Li, masanin ilimin halitta, tare da haɗin gwiwar Juan Carlos Izpisua Belmonte, masanin ilimin halitta a Cibiyar Salk.A halin yanzu shi malami ne mai ziyara a KAUST kuma ya ba da shawarar cewa masana kimiyyar halittu su inganta rahotanni masu dacewa Da kuma sarrafawa da hanyoyin aunawa, ban da yin amfani da kayan aiki na musamman don sarrafa yanayin al'ada na nau'in tantanin halitta daban-daban.Mujallolin kimiyya yakamata su kafa ma'auni na rahoto kuma suna buƙatar isasshen kulawa da sarrafa acidity na kafofin watsa labarai, narkar da iskar oxygen da carbon dioxide.
"Mafi kyawun rahoto, aunawa, da sarrafa yanayin muhalli na al'adar tantanin halitta ya kamata ya inganta ikon masana kimiyya don sake maimaitawa da sake haifar da sakamakon gwaji," in ji Alsolami."Duba na kusa zai iya fitar da sabbin bincike da kuma kara dacewa da bincike na musamman ga jikin dan adam."
“Al’adun sel masu shayarwa shine tushen samar da alluran rigakafin ƙwayoyin cuta da sauran fasahohin halittu,” in ji masanin kimiyyar ruwa Shannon Klein."Kafin a gwada dabbobi da mutane, ana amfani da su don nazarin ilmin halitta na asali na kwayar halitta, maimaita hanyoyin cututtuka, da kuma nazarin guba na sababbin mahadi."
Klein, SG, da sauransu. (2021) Babban sakaci na kula da muhalli a cikin al'adun sel masu shayarwa na buƙatar ayyuka mafi kyau.Injiniyan Halittar Halitta.doi.org/10.1038/s41551-021-00775-0.
Tags: B cell, cell, cell al'ada, incubator, mammalian cell, masana'antu, oxygen, pH, physiology, preclinical, bincike, T cell
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Lokacin aikawa: Satumba-07-2021